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Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
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Initiation of Translation02:33

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Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
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Initiation of Translation02:33

Initiation of Translation

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Fischer Projections02:18

Fischer Projections

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Learning to draw Fischer projections of molecules and understanding their relevance plays a crucial role in the visual depiction of organic molecules. A Fischer projection is a two-dimensional projection on a planar surface to simplify the three-dimensional wedge–dash representation of molecules. This is especially helpful in the case of molecules with multiple chiral centers that can be difficult to draw. Here, all the bonds of interest are represented as horizontal or vertical lines. While...
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Newman Projections02:06

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Different notations are used to represent the three-dimensional structure of molecules on two-dimensional surfaces. One of the most commonly used representations is the dash-wedge formula. The dashed wedges, solid wedges, and the plane lines indicate the groups situated behind the plane, coming out of the plane, and in the plane, respectively.
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Transcription Initiation01:47

Transcription Initiation

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Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
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The Philadelphia Autism Project Model: Lessons Learned from Developing a Citywide Autism Initiative.

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    Progress in Community Health Partnerships : Research, Education, and Action
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    The Philadelphia Autism Project, developed by autistic individuals and stakeholders, offers a replicable model for community-led autism support. Key lessons include fostering trust, ensuring collaboration, and planning for sustainability.

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    Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
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    Area of Science:

    • Community-based participatory research
    • Autism research and support
    • Public health initiatives

    Background:

    • Rising autism prevalence necessitates inclusive research and support initiatives.
    • The Philadelphia Autism Project was co-developed by autistic individuals, families, and community stakeholders.
    • Existing autism initiatives often fail to adequately include autistic individuals.

    Purpose of the Study:

    • To examine the development, partnerships, lessons learned, and impact of a citywide autism project.
    • To utilize an ecological framework and community-academic approach to understand project dynamics.
    • To provide a replicable model for community-driven autism support.

    Main Methods:

    • A community-academic partnership approach guided project development.
    • Engaged autistic individuals, families, and multi-system stakeholders.
    • Applied an ecological framework to analyze stakeholder roles, governance, and sustainability.

    Main Results:

    • Mobilizing diverse champions is crucial for project success.
    • Strategic planning for long-term sustainability is essential.
    • Sufficient time must be dedicated to building trust among partners.
    • Collaborative governance and equitable power-sharing are vital.

    Conclusions:

    • The Philadelphia Autism Project model successfully fostered meaningful collaborations for autistic individuals.
    • The project utilized an ecological framework to enhance support systems.
    • This model offers a replicable approach for other communities seeking to improve autism support.