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Related Concept Videos

Development of the Lymphatic System01:15

Development of the Lymphatic System

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The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
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The muscles of the pelvic floor and perineum are crucial for supporting the pelvic organs, controlling continence, and aiding in sexual function, childbirth, and core stability. They are typically divided into the superficial perineal layer and the deep pelvic floor layer.
Perineal Layer
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Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
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Functions of the Lymphatic and Immune System01:28

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The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
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Lymphatic Vessels and Lymph Transport01:16

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Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
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Atoms — and the protons, neutrons, and electrons that compose them — are extremely small. For example, a carbon atom weighs less than 2 × 10−23 g. When describing the properties of tiny objects such as atoms, we use appropriately small units of measure, such as the atomic mass unit (amu). The amu was originally defined based on hydrogen, the lightest element, then later in terms of oxygen. Since 1961, it has been defined with regard to the most abundant isotope of carbon, atoms of which...
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Updated: Feb 4, 2026

Author Spotlight: Unveiling Cellular Functions and Potential Clinical Implications of Leptomeningeal Lymphatic Endothelial Cells
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Primary lymphatic leiomyosarcoma presenting as a pelvic mass.

Bridget S Dillon1, Rayan M Sibira2, Laura Miller1

  • 1Department of Obstetrics and Gynecology and Women's Health, University of Minnesota, Minneapolis, MN, USA.

Gynecologic Oncology Reports
|February 2, 2026
PubMed
Summary

This case report details a rare instance of lymphatic-confined leiomyosarcoma (LMS) in a 72-year-old woman. The patient achieved disease-free status for 16 months following surgical resection and aromatase inhibitor therapy.

Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Leiomyosarcoma (LMS) typically originates in the uterus or retroperitoneum.
Keywords:
Enlarged obturator lymph nodeLymphatic leiomyosarcoma

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  • Lymph node metastasis from LMS is exceptionally rare, with no prior reports of lymphatic-confined LMS.
  • A 72-year-old woman with a history of hysterectomy presented with pelvic mass and extensive lymphadenopathy.