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Updated: Feb 4, 2026

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Case Report: Anlotinib for advanced chordoma

Zhining Jing1, Chunmiao Song1, Yongqiang Jiang1

  • 1Department of Neurosurgery, Baotou Central Hospital, Affiliated Baotou Clinical College of inner Mongolia Medical University, Baotou, Inner Mongolia, China.

Frontiers in Oncology
|February 2, 2026
PubMed

Insights

Anlotinib offers potential relief for advanced chordoma patients ineligible for surgery. This targeted therapy demonstrated a partial response, managing symptoms and tumor progression in a thoracic chordoma case.

Area of Science:

  • Oncology
  • Medical Research

Background:

  • Chordoma is a rare, low-to-moderate malignancy tumor.
  • Early-stage chordoma is treated with surgical resection.
  • Advanced-stage diagnosis often precludes surgery due to slow growth and local invasiveness.
Keywords:
advanced canceranlotinibcase reportchordomamolecular targeted drugs

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