Clinical, Echocardiography, biochemical and MRI findings in patients with acute left ventricular dysfunction to

Deen Dayal Nagar1, Varsha Shrivastava2, Yamini Batham3

  • 1Department of Pediatric Cardiology, Sawai Man Singh Medical College and J K Lone Hospital, Jaipur, Rajasthan, India.

Bioinformation
|February 2, 2026
PubMed

Insights

Pediatric heart failure, though rare, affects young children and differs from adult presentations. Key factors like older age and low ejection fraction predict poor short-term outcomes in children with acute left ventricular dysfunction.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Research
  • Clinical Medicine

Background:

  • Heart failure in children is uncommon but serious, impacting younger patients.
  • Clinical presentation and caregiver needs differ significantly from adult heart failure.
  • Early outcome prediction in pediatric acute left ventricular dysfunction requires comprehensive assessment.

Purpose of the Study:

  • To identify predictors of short-term outcomes in pediatric patients with severe acute left ventricular dysfunction.
  • To analyze clinical, echocardiographic, biochemical, and cardiac MRI data for prognostic value.

Main Methods:

  • Retrospective study of 60 children and adolescents (1 month to 18 years) with severe acute LV dysfunction.
  • Data collected included age, left ventricular ejection fraction (LVEF), ionotropic support, intracardiac thrombus, and hospital stay.
  • Utilized clinical, echocardiographic, biochemical, and cardiac MRI findings for analysis.

Main Results:

  • Older age at admission was associated with poorer outcomes.
  • Low LVEF on admission and need for ionotropic support were negative prognostic indicators.
  • Presence of intracardiac thrombus and longer hospital stay also predicted adverse short-term results.

Conclusions:

  • Several factors, including older age, low LVEF, ionotropic support, intracardiac thrombus, and prolonged hospitalization, are poor predictors of short-term outcomes in pediatric acute left ventricular dysfunction.
  • These findings highlight the need for careful monitoring and management in this vulnerable population.

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