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Racial disparities in transcatheter aortic valve replacement: A contemporary nationwide analysis

Charley Sun1, Michael Zhu1, Daniel McGrath2

  • 1Tufts University School of Medicine, United States.

American Heart Journal Plus : Cardiology Research and Practice
|February 2, 2026
PubMed

Insights

Transcatheter aortic valve replacement (TAVR) is safe for all races, with similar mortality rates. However, non-White patients experienced more complications, suggesting disparities in TAVR access and outcomes.

Area of Science:

  • Cardiovascular Medicine
  • Health Disparities Research
  • Interventional Cardiology

Background:

  • Racial disparities in cardiovascular disease management are a documented concern.
  • Transcatheter aortic valve replacement (TAVR) volume is increasing, with expanding indications.
  • Understanding contemporary racial disparities in TAVR is crucial.

Purpose of the Study:

  • To evaluate potential racial disparities in TAVR access and outcomes.
  • To compare TAVR patient characteristics and in-hospital results by race.
  • To assess TAVR safety and effectiveness across racial groups.

Main Methods:

  • Analysis of the National Inpatient Sample (2016-2019) for patients aged ≥18 undergoing TAVR.
  • Comparison of baseline characteristics and in-hospital outcomes between White and non-White patients.
  • Propensity-score matching to control for confounding factors.

Main Results:

  • No significant difference in in-hospital mortality or composite outcomes between White and non-White patients.
  • Non-White patients had higher rates of acute renal failure, transfusion, and vascular complications.
  • Non-White patients had lower rates of permanent pacemaker implantation.

Conclusions:

  • TAVR is a safe procedure with comparable in-hospital outcomes for White and non-White patients.
  • Observed differences in complications suggest racial disparities in TAVR accessibility and post-procedure care.
  • Further research is needed to address identified disparities in TAVR outcomes.
Abstract

Keywords:
AccessibilityMortalityOutcomeRacial disparityTranscatheter aortic valve replacement

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