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Echocardiographic reference values in elderly with a focus on octogenarians and older
Miguel Quintana1,2,3, Mira Carling1, Anders Olofsson3
1Karolinska Institutet, Institution of Laboratory Medicine, Stockholm, Sweden.
International Journal of Cardiology. Heart & Vasculature
|February 2, 2026
Summary
Echocardiographic reference values differ significantly in individuals aged 80 and older compared to younger groups, particularly in diastolic and systolic function. Updated, age-adapted values are crucial for accurate diagnosis in the elderly.
Area of Science:
- Cardiology
- Geriatric Medicine
- Medical Imaging
Background:
- Published echocardiographic reference values often exclude individuals over 60-70 years.
- Reference values for healthy octogenarians and older adults are scarce.
- Accurate interpretation requires updated values reflecting healthy aging.
Purpose of the Study:
- To compare transthoracic echocardiographic reference values in healthy octogenarians and older individuals with younger age groups.
- To establish age-adapted reference values for improved diagnostic accuracy in the elderly.
Main Methods:
- A total of 248 individuals were studied.
- Participants were categorized into three age groups: sexagenarians, septuagenarians, and octogenarians or older.
- Standard transthoracic echocardiographic examinations were performed according to current guidelines.
Main Results:
- Statistically significant differences were observed in echocardiographic parameters, especially those reflecting left ventricular diastolic function.
- A significant decrease in mitral annular plane systolic excursion was noted in octogenarians compared to younger groups.
- Differences in systolic function parameters were also found between age groups.
Conclusions:
- Echocardiographic parameters show significant age-related differences, particularly in diastolic and systolic function.
- Existing reference values may not be accurate for individuals aged 80 and above.
- Age-adapted reference values are essential for enhancing diagnostic accuracy in the elderly population.
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