Pediatric early warning score and unplanned readmission with influenza at emergency observation room

Wanting Xu1,2,3,4, Anji Liu1,2,3, Wen Xu1,2,3

  • 1Department of Neonatology, Children's Medical Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Frontiers in Pediatrics
|February 2, 2026
PubMed

Insights

Pediatric Early Warning Scores (PEWS) can predict unplanned readmissions in children with influenza. Higher PEWS scores indicate increased risk, suggesting PEWS is a valuable tool for improving pediatric care.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Clinical Prediction Models

Background:

  • Influenza in children can lead to clinical deterioration and unplanned readmissions.
  • The utility of Pediatric Early Warning Scores (PEWS) in predicting these readmissions requires further investigation.

Purpose of the Study:

  • To evaluate the predictive value of PEWS for identifying children with influenza at risk of unplanned readmission within 72 hours.

Main Methods:

  • A single-center case-control study included 196 children diagnosed with influenza.
  • PEWS scores were analyzed using receiver operating characteristic curves to assess their correlation with readmission likelihood.

Main Results:

  • Each 1-point increase in PEWS significantly elevated the risk of unplanned readmission (adjusted OR 10.53).
  • A PEWS cutoff score of 3 demonstrated high specificity (96.6%) and sensitivity (61.2%) for predicting readmissions.
  • Children with unplanned readmissions were less likely to have received oseltamivir (20.41% vs. 68.03%).

Conclusions:

  • PEWS shows potential for predicting unplanned readmissions in pediatric influenza cases.
  • Implementing PEWS may enhance patient management and improve outcomes for children with influenza.
Abstract

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