Related Experiment Video
Updated: Feb 4, 2026

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
Pediatric early warning score and unplanned readmission with influenza at emergency observation room
Wanting Xu1,2,3,4, Anji Liu1,2,3, Wen Xu1,2,3
1Department of Neonatology, Children's Medical Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Insights
Pediatric Early Warning Scores (PEWS) can predict unplanned readmissions in children with influenza. Higher PEWS scores indicate increased risk, suggesting PEWS is a valuable tool for improving pediatric care.
Area of Science:
- Pediatrics
- Infectious Diseases
- Clinical Prediction Models
Background:
- Influenza in children can lead to clinical deterioration and unplanned readmissions.
- The utility of Pediatric Early Warning Scores (PEWS) in predicting these readmissions requires further investigation.
Purpose of the Study:
- To evaluate the predictive value of PEWS for identifying children with influenza at risk of unplanned readmission within 72 hours.
Main Methods:
- A single-center case-control study included 196 children diagnosed with influenza.
- PEWS scores were analyzed using receiver operating characteristic curves to assess their correlation with readmission likelihood.
Main Results:
- Each 1-point increase in PEWS significantly elevated the risk of unplanned readmission (adjusted OR 10.53).
- A PEWS cutoff score of 3 demonstrated high specificity (96.6%) and sensitivity (61.2%) for predicting readmissions.
- Children with unplanned readmissions were less likely to have received oseltamivir (20.41% vs. 68.03%).
Conclusions:
- PEWS shows potential for predicting unplanned readmissions in pediatric influenza cases.
- Implementing PEWS may enhance patient management and improve outcomes for children with influenza.
Background:
This study explored the predictive value of the pediatric early warning scores (PEWS) in recognizing clinical deterioration and identifying children with influenza with unplanned readmission to the emergency observation room (EOR) within 72 h.
Methods:
A total of 196 children were included in this single-center case-control study conducted between 1 January and 30 June 2024. PEWS scores and receiver operating characteristic curves were used to evaluate the correlations between the scores and the likelihood of influenza necessitating readmission.
Results:
For each 1-point increase in PEWS score, the risk of unplanned readmission significantly increased with unadjusted PEWS of [OR 9.98 (1.54-64.73); P = 0.016] and adjusted PEWS of [OR 10.53 (3.47-31.98); P < 0.001], respectively. The time to reach the highest PEWS was significantly longer in patients who experienced unplanned readmissions (P < 0.01). Among the non-readmitted patients, 100 out of 147 (68.03%) took oseltamivir orally, compared with only 10 out of 49 (20.41%) patients with unplanned readmissions within 72 h (P < 0.001). A PEWS cutoff score of 3 indicated a relatively high sensitivity of 61.2% and specificity of 96.6%, with a positive likelihood ratio (PLR) of 18.0 and a negative likelihood ratio of 0.4.
Conclusions:
PEWS is potential for predicting unplanned readmissions with similar symptoms in children with influenza, demonstrating it may be an essential tool for enhancing patient care and outcomes.
More Related Videos
Related Concept Videos
Emerging Adulthood
Introduction to z Scores
z scores...
Introduction to z Scores
z scores...
z Scores and Area Under the Curve
Naturalistic Observations
Introduction Cardiac Emergencies

