PRO-KIND consensus protocol for classification, monitoring, and therapy in pediatric rheumatology: persistent

Joachim Peitz1, Gerd Horneff1, Anna Raab2

  • 1Pediatric Rheumatology Center, Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany.

Frontiers in Pediatrics
|February 2, 2026
PubMed

Insights

Standardized protocols for classifying, monitoring, and treating oligoarticular juvenile idiopathic arthritis (JIA) were created. These evidence-based guidelines aim to optimize care for children with persistent JIA.

Area of Science:

  • Pediatric Rheumatology
  • Clinical Protocol Development

Background:

  • Juvenile idiopathic arthritis (JIA) is a complex condition requiring standardized management.
  • Persistent oligoarticular JIA presents unique challenges in classification, monitoring, and treatment.

Purpose of the Study:

  • To establish evidence-based, standardized protocols for managing persistent oligoarticular JIA.
  • To optimize the treatment of newly occurring and persistent oligoarticular JIA through consensus.

Main Methods:

  • A consensus process involving medical members of the Society for Paediatric and Adolescent Rheumatology (GKJR).
  • Development of 23 initial statements, followed by an online survey of 80 pediatric and adolescent rheumatologists (65% participation).
  • Incorporation of survey feedback in a final online meeting to agree on 20 statements and a consensus treatment protocol.

Main Results:

  • Development of 20 consensus statements for newly occurring oligoarticular JIA.
  • Creation of a summary consensus treatment protocol for persistent oligoarticular JIA.
  • Achieved agreement among a significant majority of active pediatric and adolescent rheumatologists.

Conclusions:

  • Standardized, evidence-based protocols are crucial for effective JIA management.
  • The developed consensus guidelines provide a framework for optimizing oligoarticular JIA care.
  • This consensus process ensures broad agreement on best practices in pediatric rheumatology.

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