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Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
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Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease

Published on: May 10, 2024

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Deciphering the Role of Sirtuin-1 Gene Polymorphism in Diabetic Nephropathy: A Systematic Review and Meta-Analysis

Hira Moin1, Munazza Asad1, Maaz Waseem2

  • 1Department of Physiology, NUST School of Health Sciences, National University of Sciences and Technology (NUST), H-12 Sector, Islamabad, Pakistan, nust.edu.pk.

Journal of Diabetes Research
|February 2, 2026
PubMed
Summary

Certain Sirtuin-1 gene (SIRT1) polymorphisms, specifically rs7895833 and rs2273773, are linked to a higher risk of diabetic nephropathy. These findings highlight SIRT1 variants as potential genetic markers for identifying individuals at increased risk.

Keywords:
diabetic nephropathygenetic susceptibilitymeta-analysispolymorphismrenal diseaserisk stratificationsirtuin-1

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