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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Chilblain lupus: A rare form of cutaneous lupus erythematosus - A case report
Gabriele Perazzolli1, Elia Banchetti1, Enrico Melis1
1Section of Dermatology and Venereology, Department of Medicine, University of Verona, Italy.
Abstract:
Chilblain lupus erythematosus is a rare, cold-induced form of chronic cutaneous lupus that can occur in both genetic and sporadic forms. It is characterized by acral skin lesions and is commonly associated with autoimmunity and type I interferon pathway activation. Diagnosis is based on clinical features and histological findings. While topical and systemic therapies can be effective, the disease is often chronic and relapsing. We describe a case of a 48-year-old woman with chilblain lupus erythematosus who achieved almost complete clinical remission following treatment with hydroxychloroquine and methotrexate.
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