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Published on: June 13, 2025
Current status and factors influencing research ethics knowledge and attitudes among pediatricians: a cross-sectional
Bingya Zheng1, Na Zhang2, Hongwen Qin3
1Department of Child Healthcare, NHC Key Laboratory of Birth Defect for Research and Prevention (Hunan Provincial Maternal and Child Health Care Hospital), Changsha, China.
Insights
Pediatricians show moderate research ethics knowledge but positive attitudes. Training significantly impacts both, while institutional factors like ethics committees influence knowledge more than attitudes.
Area of Science:
- Medical Ethics
- Pediatric Research
- Clinical Research
Background:
- Pediatricians are crucial for hospital-based research and pediatric discipline advancement.
- Ensuring research ethics is paramount due to the pediatric population's unique vulnerabilities.
- Acquiring research ethics knowledge is vital for pediatricians to protect subjects and standardize practices.
Purpose of the Study:
- To assess pediatricians' knowledge and attitudes toward research ethics.
- To identify factors influencing pediatricians' research ethics knowledge and attitudes.
Main Methods:
- A cross-sectional survey was conducted among 256 pediatricians in Hunan Province, China.
- Data were collected using a general information form and a research ethics knowledge and attitude questionnaire.
- Convenience sampling was employed between October 2023 and April 2024.
Main Results:
- Pediatricians achieved an average research ethics knowledge score of 70.55 and an attitude score of 92.87.
- Key factors influencing knowledge included degree, technical title, and ethics committee presence.
- Training in ethical knowledge, research project involvement, and leadership roles influenced attitudes.
Conclusions:
- Pediatricians exhibit moderate research ethics knowledge and positive attitudes.
- Participation in ethical knowledge training positively affects both knowledge and attitudes.
- Factors like academic degree, professional title, and institutional ethics committees significantly impact research ethics knowledge.
Background:
Pediatricians play a pivotal role in clinical research, and their research competence is essential for advancing hospital-based studies and fostering the development of pediatric disciplines. Given the unique vulnerabilities of the pediatric population, adherence to research ethics is of paramount importance. Therefore, it is imperative for pediatricians to actively acquire knowledge related to research ethics in order to safeguard research quality, ensure the safety of research subjects, and enhance the standardization of ethical practices in research.
Methods:
A cross-sectional survey was conducted among 256 pediatricians in Hunan Province, China, between October 2023 and April 2024 using a convenience sampling approach. Data were collected through a general information form and a questionnaire assessing pediatricians' knowledge of and attitudes toward research ethics.
Results:
The total research ethics knowledge score for the pediatricians was 70.55, and the total attitude score was 92.87. The three lowest-scoring entries in the knowledge dimension were the basic principles of medical ethics and two situational judgment questions. The results of the multiple linear regression analysis showed that degree, technical title, whether there was an ethics committee in our hospital, and whether they participated in training related to ethical knowledge were the four factors influencing the knowledge of research ethics (F = 9.270, p < 0.001, R2 = 18.3%). The number of clinical research projects attended, the number of clinical research projects chaired, and whether or not they had participated in training related to ethical knowledge were the three factors influencing attitude toward research ethics (F = 4.259, p < 0.001, R2 = 7.80%).
Conclusion:
Pediatricians demonstrated a moderate level of research ethics knowledge but held largely positive attitudes. Whether or not they attended training related to ethical knowledge affected both knowledge and attitude scores. Notably, degree, technical title, and the presence of an ethics committee in our institution affected the knowledge score but not the attitude score.
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