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Related Experiment Video

Updated: Feb 4, 2026

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

Published on: October 4, 2015

Ultrasound-transparent neural interfaces for multimodal interaction.

Raphael Panskus^1,2, Andrada Iulia Velea^1,2, Lukas Holzapfel²

¹Department of Microelectronics, Faculty of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands.

Npj Flexible Electronics

|February 2, 2026

Summary

This summary is machine-generated.

Researchers developed flexible, ultrasound-transparent neural interfaces compatible with functional ultrasound imaging (fUSI). This breakthrough enables simultaneous brain monitoring and intervention, advancing neuroscience and neurotechnology.

Keywords:

Electrical and electronic engineering Materials for devices

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Last Updated: Feb 4, 2026

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Voltage Biasing, Cyclic Voltammetry, & Electrical Impedance Spectroscopy for Neural Interfaces

Voltage Biasing, Cyclic Voltammetry, & Electrical Impedance Spectroscopy for Neural Interfaces

Published on: February 24, 2012

Area of Science:

Neuroscience
Biotechnology
Medical Devices

Background:

Neural interfaces are crucial for neuroscience and neurotechnology.
Functional ultrasound imaging (fUSI) offers high-resolution brain monitoring.
Existing microelectrodes hinder fUSI compatibility due to ultrasound impedance.

Purpose of the Study:

To create flexible neural interfaces transparent to ultrasound.
To enable seamless integration of diagnostic and therapeutic functionalities.
To advance multimodal neural interfaces for research and clinical applications.

Main Methods:

Developed a theoretical and simulation framework to assess acoustic transparency of polymers and metals.
Proposed design guidelines for maximizing ultrasound transmission in soft neural interfaces.
Experimentally validated acoustic transparency using immersion tests, phantom studies, and in vivo fUSI.

Main Results:

Demonstrated flexible neural interfaces with high acoustic transparency.
Validated the effectiveness of the proposed design guidelines.
Confirmed compatibility with functional ultrasound imaging (fUSI) in phantom and in vivo settings.

Conclusions:

Established a foundation for multimodal neural interfaces combining diagnostics and therapeutics.
Paved the way for enhanced scientific discovery and translational impact in neurotechnology.
Highlighted potential for extension to therapeutic focused ultrasound (FUS).