Related Experiment Video
Updated: Feb 4, 2026

Generation of a Human iPSC-Based Blood-Brain Barrier Chip
Published on: March 2, 2020
Droplet Generation During Mastoidectomy and Mitigation by Use of a Novel Barrier Drape
Wei Li Neo1, Jiunfong Thong2, Heng Wai Yuen3
1Otolaryngology - Head and Neck Surgery, Sengkang General Hospital, Singapore, SGP.
Objective:
This study aims to investigate the degree of contamination generated by mastoid drilling and the extent to which this is mitigated by the use of a novel barrier drape, Otodome, which contains the surgical field.
Study Design:
Cortical mastoidectomy with a high-speed self-irrigating drill was performed under three test conditions in the cadaveric lab, including A, without a microscope, B, with a microscope alone and C, with a microscope fitted with the Otodome. Schülke Optics fluorescent solution was used as irrigation fluid.
Setting:
High-speed irrigation drills used during mastoidectomy create large amounts of droplet dispersion. This study quantifies the amount of droplet dispersion and the extent to which the barrier drape mitigates it.
Methods:
The degree (mild, moderate or severe), distribution, and distance of contamination of the surroundings were collected in each test condition. The extent of contamination of the surgeon was noted.
Results:
Condition A had the worst contamination of both the surgeon and surroundings, with the furthest distance and heaviest density of droplet spread after a cortical mastoidectomy. Droplets were dispersed up to 290cm from the surgical field. Using the barrier drape in Condition C significantly reduced the droplet dispersion to a maximum of 78cm from the surgical field. There was a significant reduction in the density of contamination of the surroundings. Most of the heavy contamination was confined within the barrier drape. There was no contamination of the surgeon's face and head region.
Conclusion:
Mastoid drilling produces an extensive amount of droplet dispersion. Improvised barrier drapes have been shown to mitigate this problem, but are cumbersome to use. The Otodome is shown to be an effective barrier drape.
Related Concept Videos
Physiological Barriers
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
Mucosal Barrier of the Stomach
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
Barriers to Effective Communication II
Cultural barriers:
Differences in values, beliefs, religion, knowledge, and tradition can significantly impact communication. Awareness of nonverbal cues is critical, especially when conversing with a patient from a different culture. What appears appropriate in one culture may be inappropriate in another.
Semantic barriers:
As a result of their tendency to use...
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The Blood-brain Barrier
Barriers to Effective Communication I
Communication barriers include the following:
Physiological barriers: They are limitations caused by a person's health condition or disability, such as hearing loss, poor eyesight, illness, or unconsciousness. An example to overcome this...

