Related Experiment Video
Updated: Feb 4, 2026
08:25
Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
Published on: April 11, 2018
15.9K
Direct-to-treatment MRI-guided prostate radiotherapy using a generic patient-agnostic reference plan.
Georgios Tsekas1, Lisa Wiersema1, Sanne Conijn1
1Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Technical Innovations & Patient Support in Radiation Oncology
|February 2, 2026
Summary
This study introduces a direct-to-treatment workflow for MRI-guided prostate radiotherapy, significantly improving efficiency. The method ensures adequate planning target volume coverage with comparable organ-at-risk sparing to traditional plans.
Area of Science:
- Radiotherapy
- Medical Physics
- Oncology
Background:
- Offline plan preparation is a major time sink in MRI-guided radiotherapy (MRIgRT).
- Patient-specific treatment planning requires extensive preparation time.
Purpose of the Study:
- To explore a patient-agnostic reference plan and delineations for direct-to-treatment (DtT) MRI-guided prostate RT.
- To eliminate patient-specific treatment preparations for MRIgRT.
Main Methods:
- Simulated a DtT workflow using data from ten prostate cancer patients.
- Created patient-specific contour adaptations and a treatment plan during fraction 1.
- Evaluated DtT plans against clinical RT plans using clinical delineations.
Main Results:
- All DtT plans achieved sufficient planning target volume (PTV) coverage (V3444cGy > 99%).
- Organ-at-risk (OAR) dose distributions were comparable to clinical plans.
- Achieved high overall efficiency gain.
Conclusions:
- The DtT workflow provides adequate PTV coverage.
- A slight increase in dose to some organs-at-risk was observed.
- The DtT workflow offers significant efficiency improvements for MRI-guided prostate radiotherapy.
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