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Related Concept Videos

Potential Energy00:52

Potential Energy

42.7K
The energy stored by a structure and location of matter in space is called potential energy. For instance, raising a kettlebell changes its spatial location and increases its potential energy. Similarly, a stretched rubber band contains potential energy which, under certain conditions, can be converted into other forms of energy, such as kinetic energy.
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
42.7K
Potential Energy01:09

Potential Energy

1.0K
A conservative force, such as a gravitational or elastic force, gives the body the capacity to do work. This capacity, measured as the potential energy, depends on the body's location or “position” relative to a fixed reference position or datum. The gravitational potential energy is considered zero at the reference point. Suppose a body is located at some vertical distance above a fixed horizontal reference or datum. In that case, the weight of the body has positive gravitational potential...
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Standard Electrode Potentials03:02

Standard Electrode Potentials

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On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
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Cell Potential and Free Energy02:58

Cell Potential and Free Energy

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Thermodynamics of a Redox Reaction
Thermodynamics is the branch of physics dealing with the relationship between heat and other forms of energy. In an electrochemical cell, chemical energy is converted into electrical energy.
Thus, a link can be predicted between cell potential, free energy change, and the equilibrium constant for the reaction. Cell potential can also be measured as the oxidant or the reducing strength, and similar acid-base strength measures are reflected in equilibrium...
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The Resting Membrane Potential01:21

The Resting Membrane Potential

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Overview
142.6K
Electric Potential and Potential Difference01:16

Electric Potential and Potential Difference

5.7K
Suppose a positive test charge moves away from a positive static charge, then the Coulomb force does positive work, and its electric potential energy decreases. The potential energy per unit charge is defined as the electric potential. The electric potential is independent of the test charge.
When a test charge moves from the initial to the final position, the electric potential difference between those positions is defined as the ratio of the change in the potential energy to the charge on the...
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Related Experiment Video

Updated: Feb 4, 2026

Orthotopic Mouse Model of Colorectal Cancer
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Potential Pathogens Associated with Colorectal Cancer.

Javad Nezhadi1,2, Hossein Samadi Kafil3,4, Farshad Mahdavi5

  • 1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Current Pharmaceutical Biotechnology
|February 2, 2026
PubMed
Summary

Gut bacteria imbalance, known as dysbiosis, promotes colorectal cancer (CRC) development. Specific pathogenic bacteria thrive in this state, driving inflammation and cancer progression, highlighting the need for microbial diagnosis and treatment in CRC management.

Keywords:
Colorectal cancercarcinogenesis.dysbiosismicrobiotapathogenic bacteriapro-inflammatory environment

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Area of Science:

  • Gastroenterology
  • Microbiology
  • Oncology

Background:

  • Colorectal cancer (CRC) originates from adenomatous polyps, progressing to invasive malignancy.
  • Gut dysbiosis, an imbalance in microbial populations, promotes a pro-inflammatory environment.
  • Certain pathogenic bacteria are linked to increased CRC risk and progression.

Purpose of the Study:

  • To investigate the role and mechanisms of specific pathogenic bacteria in colorectal cancer (CRC) development.
  • To understand how these bacteria influence cellular and immune changes during CRC.
  • To emphasize the significance of diagnosing and treating these microorganisms in CRC patients.

Main Methods:

  • Literature review and analysis of existing research on gut microbiota and CRC.
  • Identification of key pathogenic bacteria associated with CRC progression.
  • Examination of proposed mechanisms linking dysbiosis to CRC pathogenesis.

Main Results:

  • Dysbiosis disrupts the gut microbiota balance, favoring pathogenic species.
  • Specific bacteria like *Fusobacterium nucleatum*, *E. coli*, and *H. pylori* are implicated in CRC.
  • These bacteria contribute to CRC by inducing inflammation and altering cellular functions.

Conclusions:

  • Pathogenic bacteria play a significant role in the development and progression of colorectal cancer.
  • Targeting these microorganisms may offer novel therapeutic strategies for CRC.
  • Further research is needed to elucidate the precise mechanisms and clinical implications.