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State-of-the-art 32 cm field-of-view digital PET/CT system: preliminary study for protocols optimization and DRLs

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The new GE Omni Legend PET/CT scanner significantly reduces injected activity by up to 60% while maintaining or improving image quality. This advancement supports optimized radiation dose levels in diagnostic imaging.

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Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Radiological Physics

Background:

  • Positron Emission Tomography/Computed Tomography (PET/CT) systems are crucial for medical diagnostics.
  • Advancements in scanner technology aim to improve image quality and reduce patient radiation dose.
  • Diagnostic Reference Levels (DRLs) require regular updates to reflect technological progress.

Purpose of the Study:

  • To evaluate the performance of the GE Omni Legend 32 cm PET/CT system.
  • To assess the impact of the new system on administered activity and image quality.
  • To update DRLs based on the new system's capabilities and clinical data.

Main Methods:

  • System performance was assessed using NEMA NU 2-2018 standards and EARL2 accreditation tests.
  • A comparative analysis was conducted between the GE Omni Legend and a GE Discovery IQ scanner.
  • Retrospective analysis of adult patient examinations was performed to derive updated DRLs.

Main Results:

  • The GE Omni Legend demonstrated superior sensitivity and Noise Equivalent Count Rate compared to the previous system.
  • Up to a 60% reduction in injected activity was achieved without compromising image quality.
  • Deep learning reconstruction further improved image quality, especially at reduced activity levels.
  • Derived DRLs were found to be lower than existing national and international benchmarks.

Conclusions:

  • The GE Omni Legend PET/CT system offers enhanced performance, allowing for significant dose reduction.
  • Artificial Intelligence-driven reconstruction techniques are beneficial for image quality at lower activities.
  • Updated DRLs facilitate radiation dose optimization in clinical PET/CT practice.