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Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
Published on: December 27, 2010
Population-Based Analysis of Synergistic Effects of Functional Disability and Comorbidities on Retention in HIV Care
Modupe Olajumoke Onigbogi1, Osaro Mgbere2,3,4, Paul Rowan5
1Department of Epidemiology, University of Texas School of Public Health, Houston, TX, USA.
Abstract:
ObjectiveThis cross-sectional study examined how types of disability and comorbidities influence retention in care (RIC) among people with HIV (PWH) in Houston/Harris County, Texas, USA.MethodsData from 1142 participants in the Houston Medical Monitoring Project (2015-2021) were analyzed. Descriptive statistics, bivariate analyses, and multivariable logistic regression were used to evaluate factors associated with RIC.ResultsApproximately 74.9% of participants were retained in care. Compared to PWH without specific comorbidities, those with dyslipidemia and kidney disease had higher odds of RIC (AOR: 2.66; 95% CI: 1.40-5.03 and AOR: 14.08; 95% CI: 1.44-138.12, respectively). PWH reporting only mobility disability had increased odds of RIC (AOR: 3.40; 95% CI: 1.33-8.71), while those reporting only visual disability had reduced odds of RIC (AOR: 0.38; 95% CI: 0.16-0.87). Durable viral suppression was strongly associated with greater RIC (AOR: 7.96; 95% CI: 5.28-11.99).ConclusionComorbidities and disability types significantly influence retention in HIV care. Tailored interventions are needed to improve RIC among PWH, particularly those with visual disabilities.
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