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Septic knee: multimodality approach
Aline Serfaty1, Elena Drakonaki2,3, Tatiane Cantarelli Rodrigues4,5,6
1Medscanlagos Radiology, Cabo Frio, Rio de Janeiro, Brazil. alineserfaty@gmail.com.
Skeletal Radiology
|February 2, 2026
Summary
Diagnosing septic arthritis of the knee is challenging due to overlapping symptoms. A multimodal imaging approach is crucial for accurate and timely diagnosis of this acute joint infection.
Area of Science:
- Orthopedics
- Infectious Diseases
- Radiology
Background:
- Septic arthritis of the knee is a severe infection potentially causing rapid cartilage destruction.
- Early diagnosis is complicated by nonspecific symptoms and overlapping conditions like crystal arthropathies.
- Synovial fluid analysis is key, but imaging is vital for comprehensive assessment and complication detection.
Purpose of the Study:
- To review the role of various imaging modalities in diagnosing knee septic arthritis.
- To highlight the importance of a stepwise, multimodality imaging strategy.
- To discuss emerging imaging technologies for improved accuracy.
Main Methods:
- Review of current literature on imaging techniques for septic arthritis of the knee.
- Discussion of radiography, ultrasound, CT, MRI, and nuclear medicine studies.
- Emphasis on a stepwise, multimodality approach.
Main Results:
- Ultrasound is sensitive for effusion and guides aspiration.
- CT is useful for cortical bone and deep soft tissue evaluation.
- MRI provides comprehensive early assessment, including bone marrow edema and occult abscesses.
- Nuclear medicine aids in complex cases and therapy monitoring.
Conclusions:
- A stepwise, multimodality imaging strategy improves diagnostic confidence and guides intervention for knee septic arthritis.
- Advances in imaging, including radiomics and hybrid imaging, show promise for enhanced accuracy.
- Prompt diagnosis and treatment are essential to prevent joint destruction.
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