Related Experiment Video
Updated: Feb 4, 2026
10:10
A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
Published on: February 3, 2016
13.9K
Cryotherapy in Relieving Arteriovenous Fistula Cannulation-Related Pain: Non- Randomised Crossover Trail
P Aboushika1, S Monisha2, T Moses Lamech3
1Lecturer in RDT, Department of Nephrology, College of Allied Health Sciences, SRM Institute of science and Technology, Tiruchirappalli, Tamil Nadu, India 621105.
Summary
Cryotherapy significantly reduces pain during arteriovenous fistula (AVF) cannulation for hemodialysis patients. This intervention offers a simple yet effective method to improve patient comfort during AVF access.
Area of Science:
- Nephrology
- Pain Management
- Vascular Access
Background:
- Pain during arteriovenous fistula (AVF) cannulation is a significant issue for patients on maintenance hemodialysis.
- Effective pain management strategies are crucial for improving patient adherence and quality of life.
Purpose of the Study:
- To evaluate the efficacy of cryotherapy in alleviating pain experienced by hemodialysis patients during AVF cannulation.
Main Methods:
- A randomized crossover study involving 111 hemodialysis patients.
- Patients received cryotherapy for four sessions, followed by four sessions of standard care (control).
- Pain was quantified using the Wong-Baker Faces Pain Rating Scale.
Main Results:
- A statistically significant reduction in perceived pain was observed when cryotherapy was applied (p=0.001).
- Cryotherapy demonstrated a clear benefit in reducing cannulation-related pain.
Conclusions:
- Cryotherapy is an effective intervention for reducing pain associated with arteriovenous fistula cannulation in hemodialysis patients.
- Implementing cryotherapy can enhance patient comfort and potentially improve the hemodialysis experience.
Related Concept Videos
01:16Crossover Experiments
4.6K
Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
4.6K
01:11Clinical Trials: Overview
5.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
01:12Trial and Error and Algorithm
420
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
420
01:16Clinical Trials
10.5K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
10.5K
01:20Pain
1.4K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.4K
01:25Analgesia and Pain Management
1.7K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.7K