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Updated: Feb 4, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Acute mitral regurgitation: The role of transcatheter edge-to-edge repair
Antonio Sisinni1, Alexandra M Rojas Sanchez1, Maurizio Tusa1
1Clinical and Interventional Cardiology Department, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Abstract:
Acute mitral regurgitation (MR) is a critical condition arising from diverse etiologies, including infective endocarditis, ischemic heart disease, stress-induced cardiomyopathy, and iatrogenic injury. While surgical repair or replacement has traditionally served as the standard of care, particularly in emergent cases, the evolution of transcatheter mitral valve therapies offers viable alternatives for patients deemed high-risk for conventional surgery. This review examines the pathophysiological mechanisms underlying acute MR in specific clinical contexts, and explores the expanding role of transcatheter edge-to-edge repair.
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