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Integrated action for skin NTDs: Deconstructing transmission, addressing knowledge gaps, and championing one health
Lydia Mosi1,2, Bishwanath Acharya3, Kingsley Asiedu4
1Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, Ghana.
Abstract:
Skin Neglected Tropical Diseases (skin NTDs) are a critical, underestimated source of chronic pathology, severely impacting vulnerable, rural populations with poor healthcare access. These diseases heighten the risk of systemic infection, amputation, and premature mortality. Their visibility and co-endemic nature present a pivotal opportunity for integrated diagnostics and management at the primary care level. Aligned with the WHO roadmap, this review advocates for a robust One Health framework, examining the complex interplay of human, animal, and environmental transmission factors. We contrast diseases with understood transmission against those requiring research. Leveraging the skin as a common pathway, we argue for strategic, integrated public health action to substantially improve patient outcomes globally.
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