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Updated: Feb 4, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Human immunodeficiency virus: a case of household transmission
Rabab AlGhaithi1, Dayel AlShahrani2, Sara AlMuhisen3
1Paediatric Infectious Disease, King Fahad Medical City, Riyadh, Saudi Arabia. ralgaithi@kfmc.med.sa.
Abstract:
Human immunodeficiency virus (HIV) infection in children is usually vertically acquired from the mother, in utero, intrapartum, or via breastfeeding. In this case, we report the probable case of horizontal transmission of HIV between two siblings. Based on the available clinical and laboratory data, perinatal, sexual, and health care-related transmission are unlikely. Although rare, this method of transmission needs to be recognized, especially in the setting of direct contact with an individual with poorly suppressed HIV viral infection.
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