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Updated: Feb 4, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
Bilateral rectus sheath hematoma following enoxaparin administration in a patient with extensive lower limb DVT: a
Rounak Mehrotra1, Amritanshu Saurabh1, Shirish Kumar1
1Department of General Surgery, All India Institute of Medical Sciences, Raebareli, India.
Abstract:
Rectus sheath hematoma (RSH) is an uncommon but potentially life-threatening complication of anticoagulant therapy. Bilateral RSH is exceedingly rare. We present a case of a middle aged woman in 40s who presented with acute onset left lower limb swelling with blisters and bluish discoloration due to extensive left lower limb deep vein thrombosis. The patient subsequently underwent emergency fasciotomy followed by above-knee amputation for ischemic limb and started on therapeutic administration of enoxaparin. During the postoperative course, the patient developed a progressive infraumbilical abdominal wall swelling at the site of subcutaneous injections, later confirmed to be bilateral rectus sheath hematomas (RSH). This report highlights the importance of recognizing this rare complication in anticoagulated patients presenting with abdominal wall masses and anaemia.
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