Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brainstem01:19

Brainstem

6.5K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
6.5K
The Auditory Ossicles01:11

The Auditory Ossicles

3.1K
The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
3.1K
Performing a Simple Data Analysis using MS-Excel Function01:17

Performing a Simple Data Analysis using MS-Excel Function

1.0K
Microsoft Excel offers a suite of functions and tools ideal for statistical analysis, making it accessible to students and researchers. This article outlines fundamental Excel functions pivotal for data analysis.
SUM: This function calculates the total sum of a range of values. It's the foundation for aggregating data, essential for determining overall trends and totals in datasets.
AVERAGE: It computes the mean value of a given set of numbers, providing a quick insight into the central...
1.0K
Auditory Pathway01:15

Auditory Pathway

7.3K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
7.3K
Sound Intensity00:58

Sound Intensity

4.8K
The loudness of a sound source is related to how energetically the source is vibrating, consequently making the molecules of the propagation medium vibrate. To measure the loudness of a source, the physical quantity of interest is the intensity. This is defined as the energy emitted per unit of time per unit of area perpendicular to the sound wave's propagation direction. Since the total energy is greater if the source vibrates for a longer duration and over a larger area, dividing the...
4.8K
Auditory Perception01:17

Auditory Perception

1.1K
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating peripheral neural processing through spectral analysis of auditory brainstem responses.

JASA express letters·2026
Same author

Maturation of Cortical Auditory Evoked Potentials in Response to Tones and Noise During Adolescence and Young Adulthood.

Journal of speech, language, and hearing research : JSLHR·2026
Same author

Contributions of Behavioral and Electrophysiological Spectrotemporal Processing to the Perception of Degraded Speech in Younger and Older Adults.

Journal of speech, language, and hearing research : JSLHR·2025
Same author

Evaluating Changes in Adult Cochlear Implant Users' Brain and Behavior Following Auditory Training.

Ear and hearing·2024
Same author

The association between electrode impedance and short-term outcomes in cochlear implant recipients of slim modiolar and slim straight electrode arrays.

Cochlear implants international·2023
Same author

The Effect of Aging on Auditory Nerve Function: Insights from Intraoperative eCAP Recordings in Cochlear Implant Users.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2023

Related Experiment Video

Updated: Feb 4, 2026

Evaluation of Auditory Brainstem Response in Chicken Hatchlings
09:32

Evaluation of Auditory Brainstem Response in Chicken Hatchlings

Published on: April 1, 2022

3.5K

Age-Related Changes in Speech Recognition Performance-Intensity Functions and Auditory Brainstem Responses.

Bruna S Mussoi1

  • 1Department of Audiology and Speech Pathology, The University of Tennessee Health Science Center, Knoxville, Tennessee, USA.

Ear and Hearing
|February 3, 2026
PubMed
Summary

Aging impairs speech recognition in noise and auditory brainstem responses (ABR). While reduced ABR wave I/V ratios suggest cochlear synaptopathy in older adults, this did not correlate with speech recognition performance, challenging current theories.

Keywords:
AgingAuditory Brainstem ResponsesCochlear synaptopathyPerformance-intensity functionsSpeech recognition

More Related Videos

Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
06:01

Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R

Published on: December 9, 2022

2.9K
In Ovo Electroporation in the Chicken Auditory Brainstem
10:14

In Ovo Electroporation in the Chicken Auditory Brainstem

Published on: June 9, 2017

9.0K

Related Experiment Videos

Last Updated: Feb 4, 2026

Evaluation of Auditory Brainstem Response in Chicken Hatchlings
09:32

Evaluation of Auditory Brainstem Response in Chicken Hatchlings

Published on: April 1, 2022

3.5K
Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
06:01

Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R

Published on: December 9, 2022

2.9K
In Ovo Electroporation in the Chicken Auditory Brainstem
10:14

In Ovo Electroporation in the Chicken Auditory Brainstem

Published on: June 9, 2017

9.0K

Area of Science:

  • Auditory Neuroscience
  • Gerontology
  • Speech Perception

Background:

  • Age-related hearing decline is multifactorial.
  • Cochlear synaptopathy is a potential peripheral auditory contributor to age-related speech recognition deficits.
  • Previous human studies on age-related cochlear synaptopathy have yielded inconclusive results.

Purpose of the Study:

  • To investigate the impact of aging on speech recognition performance-intensity functions in noise and high-level auditory brainstem responses (ABRs).
  • To examine the association between these measures in younger and older adults.
  • To assess the role of cochlear synaptopathy in age-related auditory changes.

Main Methods:

  • Nineteen younger (18-36 yrs) and 19 older adults (65-81 yrs) with normal audiometry participated.
  • Speech recognition performance-intensity functions were measured using words in multitalker babble across various signal-to-noise ratios (SNRs).
  • High-level auditory brainstem responses (ABRs) were recorded at two presentation rates (11.3/sec and 41.3/sec) using click stimuli.

Main Results:

  • Older adults required more favorable SNRs for equivalent speech recognition performance compared to younger adults.
  • A reduction in ABR wave I/V amplitude ratios was observed in older adults, consistent with cochlear synaptopathy.
  • No significant association was found between speech recognition performance-intensity function metrics and ABR I/V amplitude ratios.

Conclusions:

  • Aging negatively affects speech recognition in noise and ABR responses.
  • While reduced ABR wave I/V ratios suggest age-related cochlear synaptopathy, this did not correlate with speech recognition performance.
  • These findings challenge the direct link between cochlear synaptopathy and observed speech recognition deficits in aging individuals.