What Evidence Do We Need to Improve the Attainment of Bladder and Bowel Control in Children and Prevent Negative Sequelae in Adolescence and Adult Life? ICI-RS 2025
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Published on: August 1, 2025
Alexander von von Gontard1, Giovanni Mosiello2, Tufan Tarcan3
1Department of Urology, Governor Kremers Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
Insights
Childhood incontinence, including nocturnal enuresis and fecal incontinence, can persist into adulthood, posing medical and mental health risks. Identifying risk and protective factors early is crucial for prevention and improved clinical care.
Area of Science:
- Pediatric Urology
- Childhood Functional Disorders
- Continence Management
Background:
- Nocturnal enuresis (NE), daytime urinary incontinence (DUI), fecal incontinence (FI), and functional constipation (FC) are prevalent childhood functional disorders.
- These conditions can persist into adolescence and adulthood, impacting long-term health and well-being.
Purpose of the Study:
- To review evidence on risk factors hindering bladder/bowel control attainment and contributing to persistent incontinence.
- To outline protective factors that minimize long-term negative sequelae of childhood incontinence.
Main Methods:
- A multidisciplinary expert think tank group from the International Consultation on Incontinence Research Society (ICI-RS) reviewed existing evidence.
- Both prospective and retrospective data were considered, with discussions on future research directions and clinical practice improvements.
Main Results:
- Childhood incontinence can extend into adulthood, associated with increased medical and mental health risks.
- Identified risk factors include genetics and environment (e.g., late toilet training, prolonged diaper use, digital media, lack of transitional care).
- Research on prevention strategies and the interaction between risk and protective factors is lacking.
Conclusions:
- Childhood incontinence often precedes adult incontinence, necessitating early preventive measures.
- Future research should prioritize identifying both risk and protective factors.
- Enhanced collaboration between pediatric services and adult urology is essential for improved patient outcomes.
Aims:
Nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) and functional constipation (FC) are common functional disorders in childhood, which can persist into adolescence and adulthood. The aim of this paper is to review evidence of risk factors that impede the attainment of bladder/bowel control and contribute towards the persistence of incontinence, and to outline protective factors towards minimizing long-term negative sequelae.
Methods:
A think tank group consisting of multidisciplinary experts at the International Consultation on Incontinence Research Society (ICI-RS) in 2025 reviewed evidence of factors influencing the attainment of bladder and bowel control, the continuation of incontinence into adolescence and adulthood and the subsequent negative sequelae. Both prospective and retrospective views were considered. Open questions and future directions were discussed. Recommendations for future research and for the improvement of clinical practice in in children, adolescents and adults were formulated.
Results:
Childhood incontinence can continue into adolescence and adulthood and is associated with medical and mental health risks. Genetic and environmental risk factors have been identified, but their interaction with protective factors has not been studied. Potentially important environmental risks that require further research include late toilet training, prolonged use of disposable diapers, excessive use of digital media and lack of transitional care from pediatric to adult services. Studies on prevention on all levels (universal, selective and indicated) are lacking.
Conclusions:
As childhood incontinence is a precursor of adult incontinence in many patients, early preventive measures are needed. Future research should focus on identifying risk and protective factors. Improved collaboration and exchange between pediatric services and adult urology is essential.
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