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Updated: Feb 4, 2026
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Feasibility and Acceptability of Remote Hair Sample Collection in Parent-Child Dyads
Tsui-Sui Annie Kao1, Jiying Ling
1Tsui-Sui Annie Kao, PhD, RN, FNP-BC, FAANP and Jiying Ling, PhD, RN, FAAN, Michigan State University, College of Nursing, East Lansing, MI.
Nursing Research
|February 3, 2026
Summary
Remote hair cortisol collection is feasible for rural families, but engagement decreases over time. Further research is needed to improve sustained participation in voluntary biospecimen collection for stress research.
Area of Science:
- Psychiatry and Psychology
- Public Health
- Biomarkers
Background:
- Chronic stress negatively impacts health and can be passed between generations.
- Hair cortisol concentration (HCC) is a biomarker for chronic stress.
- Feasibility and acceptability of remote HCC collection in rural families are not well understood.
Purpose of the Study:
- Evaluate the feasibility and acceptability of remote hair sample collection in rural families.
- Identify factors associated with hair sample completion.
- Assess the preliminary effects of a family-centered intervention on HCC.
Main Methods:
- Pilot randomized trial with 46 rural parent-child dyads.
- Optional remote hair sample collection at baseline and post-intervention.
- Intervention group received mindfulness-based motivational interviewing; control group received active control.
Main Results:
- 78% consented to hair collection; 67% returned baseline samples, 50% returned post-intervention samples.
- Instructions were clear; no participants used remote support.
- No significant demographic associations with completion, but trends noted for minority and employed parents.
Conclusions:
- Optional remote HCC collection is feasible and acceptable for many rural families.
- Participant retention decreased over time.
- Future studies should focus on strategies to enhance sustained engagement in voluntary biospecimen collection.
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