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Green laboratory through test ordering appropriateness and innovation
Sveva Stangalini1, Sara Sacchetti1,2, Paolo Tillio1
1Clinical Chemistry Laboratory, 9256 "Maggiore Della Carità" University Hospital , Novara, Italy.
Clinical Chemistry and Laboratory Medicine
|February 3, 2026
Summary
Clinical laboratory waste from excessive blood collection and unnecessary testing creates significant environmental and financial burdens. Implementing pre-analytical interventions can prevent over 40 tonnes of waste and save €60,800 annually.
Area of Science:
- Clinical Laboratory Medicine
- Environmental Science
- Healthcare Management
Background:
- Clinical laboratories are essential but resource-intensive, facing challenges from high energy/water use, single-use plastics, and biomedical waste.
- Current practices in clinical laboratory medicine contribute to substantial environmental and economic burdens.
Purpose of the Study:
- To quantify the environmental and economic impact of common, avoidable practices in clinical laboratory medicine.
- Focus on excessive blood collection, inappropriate test ordering, and redundant tube use in pre-analytical workflows.
Main Methods:
- Analysis of real-world data from a Clinical Biochemistry Laboratory (2024).
- Quantification of environmental and economic impact of inappropriate test ordering based on retesting intervals.
- Assessment of pre-analytical practices including redundant sample tube collection and excessive blood volumes.
Main Results:
- Inappropriate retesting generated 2,931 unnecessary tubes (26.7 kg waste).
- Redundant EDTA tubes for specific tests resulted in 356.14 kg excess waste, preventable by sample consolidation.
- Hematology and biochemistry tests generated 2.62 and 36.98 tonnes of waste, respectively.
Conclusions:
- Excessive blood collection and unnecessary test repetition create significant, avoidable environmental and financial burdens.
- Pre-analytical interventions like reducing tube volume and consolidating tests can prevent over 40 tonnes of waste and save >€60,800 annually in a single lab.
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