Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Design Example: Strain Gauge Bridge or Wheatstone Bridge01:15

Design Example: Strain Gauge Bridge or Wheatstone Bridge

1.0K
The utilization of strain gauges as transducers for converting mechanical strain into electrical signals is a common practice in various engineering applications. These strain gauges are frequently integrated into Wheatstone bridge circuits to accurately measure parameters such as force or pressure. Within this context, each element within the circuit exhibits a resistance that undergoes subtle variations when subjected to mechanical strain. The primary objective is to convert minuscule...
1.0K
Wheatstone Bridge01:29

Wheatstone Bridge

1.2K
An ohmmeter is a resistance-measuring device. It works by applying a voltage to a resistor of unknown resistance and measuring the current across the resistor. The resistance value is deduced using Ohm's law. Usually, the standard configuration of an ohmmeter comprises a voltmeter or an ammeter. However, such configurations are limited in accuracy because the meters alter the voltage applied to the resistor and the current that flows through it.
Thus, for accurate resistance measurements, a...
1.2K
Bridge rectifier01:24

Bridge rectifier

1.6K
The bridge rectifier is essential in electronics for efficiently converting alternating current (AC) to direct current (DC). Comprised of four diodes configured in a bridge layout, this rectifier effectively processes both the positive and negative halves of the AC waveform, making it superior to half-wave and full-wave center-tapped rectifiers in terms of voltage regulation and output stability.
Operationally, the bridge rectifier allows current flow through two of its diodes during each...
1.6K
Genomics02:02

Genomics

40.7K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.7K
Cross-bridge Cycle01:26

Cross-bridge Cycle

122.7K
As muscle contracts, the overlap between the thin and thick filaments increases, decreasing the length of the sarcomere—the contractile unit of the muscle—using energy in the form of ATP. At the molecular level, this is a cyclic, multistep process that involves binding and hydrolysis of ATP, and movement of actin by myosin.
122.7K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.2K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Xianglian Pill combined with 5-fluorouracil enhances antitumor activity and reduces gastrointestinal toxicity in gastric cancer by regulating the p38 MAPK/NF-κB signaling pathway.

Journal of ethnopharmacology·2024
Same author

Topical Ophthalmic Liposomes Dual-Modified with Penetratin and Hyaluronic Acid for the Noninvasive Treatment of Neovascular Age-Related Macular Degeneration.

International journal of nanomedicine·2024
Same author

Screening Efficient C-N Coupling Catalysts for Electrosynthesis of Acetamide and Output Ammonia through a Cascade Strategy of Electrochemical CO<sub>2</sub> and N<sub>2</sub> Reduction Using Cu-Based Nitrogen-Carbon Nanosheets.

ACS applied materials & interfaces·2024
Same author

The significance of gut microbiota in the etiology of autoimmune hepatitis: a narrative review.

Frontiers in cellular and infection microbiology·2024
Same author

Modulating Inorganic Dimensionality of Ultrastable Lead Halide Coordination Polymers for Photocatalytic CO<sub>2</sub> Reduction to Ethanol.

Angewandte Chemie (International ed. in English)·2024
Same author

BTK Expression Level Prediction and the High-Grade Glioma Prognosis Using Radiomic Machine Learning Models.

Journal of imaging informatics in medicine·2024

Related Experiment Video

Updated: Feb 4, 2026

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
08:31

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'

Published on: May 26, 2013

11.5K

eQTL analysis: A bridge from genome to mechanism.

Zhe Jia1, Jing Xu1, Yingnan Ma1

  • 1College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150086, China.

Genes & Diseases
|February 3, 2026
PubMed
Summary

Expression quantitative trait loci (eQTLs) link genetic variations to gene expression, aiding in understanding complex traits and diseases. Integrating eQTLs with other omics data reveals novel genes and regulatory mechanisms.

Keywords:
Expression quantitative trait locusGene expressionGenetic variationGenome-wide association studySingle nucleotide polymorphism

More Related Videos

Ultra-long Read Sequencing for Whole Genomic DNA Analysis
10:34

Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

24.0K
Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes
08:56

Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes

Published on: July 27, 2018

11.5K

Related Experiment Videos

Last Updated: Feb 4, 2026

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
08:31

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'

Published on: May 26, 2013

11.5K
Ultra-long Read Sequencing for Whole Genomic DNA Analysis
10:34

Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

24.0K
Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes
08:56

Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes

Published on: July 27, 2018

11.5K

Area of Science:

  • Genomics
  • Systems Biology
  • Genetic Epidemiology

Background:

  • Expression quantitative trait loci (eQTLs) are genetic variations influencing gene expression.
  • eQTL analysis is crucial for deciphering the genetic basis of complex traits and diseases.
  • eQTLs have been identified across various tissues and single cells.

Purpose of the Study:

  • To provide a comprehensive review of expression quantitative trait loci (eQTLs).
  • To cover eQTL identification methods, analysis tools, and data resources.
  • To discuss the role of eQTLs in disease mechanisms and future research directions.

Main Methods:

  • Literature review of eQTL identification and analysis methodologies.
  • Synthesis of current research progress in the field of eQTLs.
  • Exploration of eQTL data integration with other omics datasets.

Main Results:

  • eQTLs provide insights into gene regulation and the genetic architecture of diseases.
  • Integration of eQTLs with multi-omics data facilitates the discovery of novel susceptibility genes.
  • eQTL studies have advanced our understanding of trait-associated genetic variations.

Conclusions:

  • eQTLs are fundamental for understanding gene expression regulation and its link to complex traits.
  • The integration of eQTL data with other omics data holds significant potential for future discoveries.
  • Future research should focus on addressing challenges and expanding the application of eQTL analysis in various biological contexts.