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Fusarium solani infection induced cardiopulmonary failure in immunocompromised patients: Two case reports

Yuanying Zeng1, Dan Chen1, Fang Yang1

  • 1Gobroad-Chunfu Institute of Hematology & Oncology, Taixin Hospital, Dongguan, China.

Medical Mycology Case Reports
|February 3, 2026
PubMed

Insights

Fusarium solani infections in immunocompromised patients lead to severe outcomes. This study details the progression of cardiopulmonary failure in two such cases, highlighting critical injury patterns.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • * Fusarium solani infections carry a high mortality rate in immunocompromised individuals.
  • * Disseminated Fusarium infections often result in multi-organ failure.
  • * The initial organ involvement and progression of cardiopulmonary injuries in Fusarium infections are not well-documented.

Purpose of the Study:

  • * To describe the development and progression of cardiopulmonary failure in patients with Fusarium solani infections.
  • * To provide detailed insights into the specific cardiopulmonary injuries associated with disseminated Fusarium infections.

Main Methods:

  • * Case report of two consecutive patients with Fusarium solani infections.
  • * Clinical data review focusing on the onset and progression of cardiopulmonary complications.

Main Results:

  • * Both patients developed progressive cardiopulmonary failure.
  • * Detailed clinical course and specific cardiopulmonary injuries were observed in both cases.

Conclusions:

  • * Fusarium solani infections can rapidly lead to severe cardiopulmonary failure in immunocompromised patients.
  • * Understanding the progression of these injuries is crucial for timely intervention and management.
Keywords:
CAR-T therapyCardiopulmonary failureFusarium infectionHSCTImmune deficiency

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