Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thoracic Aorta01:15

Thoracic Aorta

1.7K
The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
1.7K
Compartment Models: Two-Compartment Model01:20

Compartment Models: Two-Compartment Model

7.1K
The two-compartment model divides the body into central and peripheral compartments to account for varying blood perfusion rates among organs and tissues, affecting drug distribution. The central compartment includes blood and highly perfused tissues with rapid drug distribution, while the peripheral compartment contains tissues with slower drug distribution. After a single IV bolus dose, the drug concentration is high in plasma and low in tissues. The drug distribution between compartments...
7.1K
The Thoracic Cage: Sternum01:17

The Thoracic Cage: Sternum

6.0K
The thoracic or rib cage forms the body's thorax (chest) portion. Its primary function in the body is to protect vital organs in the thoracic cavity, such as the heart and the lungs. It consists of 12 pairs of ribs with their costal cartilages and the sternum. The ribs are anchored posteriorly to the 12 thoracic vertebrae (T1-T12).
The sternum is the elongated bony structure on the anterior side of the thoracic cage. It consists of three parts: the manubrium, the body, and the xiphoid...
6.0K
The Thoracic Cage: Ribs01:20

The Thoracic Cage: Ribs

8.7K
Ribs are curved, flattened bones forming the thoracic cavity wall with the thoracic muscles. There are 12 pairs of thoracic ribs. The posterior ends of all the ribs articulate with the T1–T12 thoracic vertebrae. In contrast,the anterior ends of most ribs attach to the sternum via their costal cartilages.
Parts of a Typical Rib
A typical rib has a head, neck, and body. The posterior end of the rib is called the head, followed by a narrow neck. The head articulates primarily with the costal...
8.7K
Relative Risk01:12

Relative Risk

2.1K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.1K
Impact of Groups on Groups01:19

Impact of Groups on Groups

249
Social psychologists analyze how groups influence one another, shaping social structures and interactions through both cooperation and competition. These dynamics manifest in various ways, ranging from economic partnerships to intergroup conflicts that shape societal structures and perceptions.Cooperation and Competition in Intergroup RelationsIntergroup relationships vary across contexts, sometimes fostering cooperation and mutual benefit while at other times leading to conflict and...
249

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A second chance for the second look: Feasibility of laparoscopic HIPEC at the conclusion of upfront treatment for epithelial ovarian cancer.

Gynecologic oncology·2026
Same author

Validation and application of automated CT analysis to musculoskeletal profiling in MVC occupants.

Traffic injury prevention·2026
Same author

Design and Validation of a Stiffness-Matched Cervical Spine Surrogate.

Annals of biomedical engineering·2026
Same author

Gene Expression Profiles at Early vs Late Stages After Cervical Artery Dissection.

Neurology. Genetics·2026
Same author

Multi-Omic, Multi-Tissue Responses to Acute Exercise in Sedentary Adults: Findings from the Molecular Transducers of Physical Activity Consortium.

bioRxiv : the preprint server for biology·2026
Same author

Feasibility of home-based, remotely delivered exercise training to improve physical function in older sepsis survivors: a pilot randomized controlled trial.

GeroScience·2026

Related Experiment Video

Updated: Feb 4, 2026

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish
08:13

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

Published on: May 31, 2021

3.7K

Multicompartment Injury Risk in High-Rate Nonpenetrating Blunt Thoracic Impacts.

Juliette Caffrey1, Fang-Chi Hsu2, F Scott Gayzik1

  • 1Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC 27101.

Journal of Biomechanical Engineering
|February 3, 2026
PubMed
Summary
This summary is machine-generated.

Blunt thoracic impacts can cause missed abdominal injuries. A finite element ovine thorax model (FE-OTM) can predict multi-compartment injury risk by analyzing impact angles and tissue strain.

More Related Videos

Controlled Cortical Impact Model for Traumatic Brain Injury
05:30

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

29.7K
Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
06:57

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome

Published on: September 13, 2020

4.1K

Related Experiment Videos

Last Updated: Feb 4, 2026

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish
08:13

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

Published on: May 31, 2021

3.7K
Controlled Cortical Impact Model for Traumatic Brain Injury
05:30

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

29.7K
Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
06:57

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome

Published on: September 13, 2020

4.1K

Area of Science:

  • Biomechanics
  • Injury Biomechanics
  • Computational Modeling

Background:

  • Blunt thoracic impacts (NPBIs) often lead to overlooked abdominal injuries, increasing mortality.
  • Unlike penetrating injuries, blunt impact locations are difficult to predict.
  • Ovine models have shown thoracic and thoracoabdominal injuries from similar impact sites.

Purpose of the Study:

  • To evaluate the finite element ovine thorax model (FE-OTM) for predicting multi-compartment injury risk.
  • To determine if impact angle influences injury risk in different thoracic compartments.
  • To develop a metric for quantifying injury risk changes based on impact parameters.

Main Methods:

  • Simulated twelve thoracic NPBIs across six impact angles (0-25°).
  • Analyzed tissue composition and strain under and along the impact path.
  • Utilized cumulative volume analysis and Spearman's rank correlation to link impact angle to a strain-volume metric.

Main Results:

  • Abdominal, lung, and liver tissues were identified as critical.
  • Strong correlations were found between impact angles and the strain-volume metric in key tissues.
  • Tissue volume changes directly corresponded to impact directionality.

Conclusions:

  • The FE-OTM effectively predicts changes in multi-compartment injury risk based on impact angle.
  • A 1st principal strain-volume metric is recommended for assessing injury risk in critical tissues.
  • This model offers a method for predicting injury patterns from blunt thoracic impacts.