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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
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Murine Model of Allergen Induced Asthma
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Metformin for asthma exacerbations.

Nurul Syafiqah Othman1,2, Amy Hy Chan1, Jeff Harrison1

  • 1School of Pharmacy, The University of Auckland, Auckland, New Zealand.

The Cochrane Database of Systematic Reviews
|February 3, 2026
PubMed
Summary
This summary is machine-generated.

This review will assess metformin's effectiveness in preventing asthma exacerbations. We aim to determine if this common diabetes medication can reduce severe asthma attacks.

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Area of Science:

  • Pulmonology
  • Pharmacology
  • Clinical Trials

Background:

  • Asthma exacerbations represent a significant burden on patients and healthcare systems.
  • Current treatments for asthma exacerbations have limitations.
  • Metformin, a widely used antidiabetic drug, has shown potential anti-inflammatory effects.

Purpose of the Study:

  • To evaluate the efficacy of metformin in reducing the frequency and severity of asthma exacerbations.
  • To synthesize evidence from randomized controlled trials on metformin for asthma management.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials.
  • Search of major biomedical databases for relevant studies.
  • Assessment of risk of bias and data synthesis.

Main Results:

  • Data synthesis is pending the identification and inclusion of relevant trials.
  • The review will quantify the effect of metformin on primary outcomes such as exacerbation rates and secondary outcomes like lung function and quality of life.

Conclusions:

  • The potential role of metformin in asthma management requires rigorous evaluation.
  • Evidence from this review will inform clinical practice and future research directions regarding metformin for asthma.