Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

3.5K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.5K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.4K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.4K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.2K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.2K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.4K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.4K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.4K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.4K
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

3.8K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Completeness of EMERGE guideline reporting in observational studies of PCSK9 inhibitor medication adherence: a study within a systematic review.

JBI evidence synthesis·2026
Same author

Implementing Digital Respiratory Technologies for People With Respiratory Conditions: Scoping Review.

Journal of medical Internet research·2026
Same author

Artificial intelligence in pain assessment and management for older adults: A scoping review.

Artificial intelligence in medicine·2026
Same author

Associations of grip strength and muscle mass with incident complications in patients with type 2 diabetes: a prospective cohort study.

Diabetes research and clinical practice·2026
Same author

Assessing Natural Health Product-Drug Interactions and Coding Feasibility: Analysis of a New Zealand General Population Dataset from an Online Market Research Panel.

Drug safety·2026
Same author

New Zealand pharmacist prescribers: a descriptive study of roles and practice.

The International journal of pharmacy practice·2026
Same journal

Interventions for smoking cessation in inpatient psychiatry settings.

The Cochrane database of systematic reviews·2026
Same journal

Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.

The Cochrane database of systematic reviews·2026
Same journal

Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.

The Cochrane database of systematic reviews·2026
Same journal

Views and experiences of weight management for people living with mobility‑limiting conditions, intellectual disabilities or severe mental illness: a qualitative evidence synthesis.

The Cochrane database of systematic reviews·2026
Same journal

Non-pharmacological interventions for anxiety and depression in Parkinson's disease.

The Cochrane database of systematic reviews·2026
Same journal

Biologic drugs for induction and maintenance of remission in Crohn's disease: a network meta-analysis.

The Cochrane database of systematic reviews·2026
See all related articles

Related Experiment Video

Updated: Feb 5, 2026

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.3K

Metformin for asthma exacerbations.

Nurul Syafiqah Othman1,2, Amy Hy Chan1, Jeff Harrison1

  • 1School of Pharmacy, The University of Auckland, Auckland, New Zealand.

The Cochrane Database of Systematic Reviews
|February 3, 2026
PubMed
Summary
This summary is machine-generated.

This review will assess metformin's effectiveness in preventing asthma exacerbations. We aim to determine if this common diabetes medication can reduce severe asthma attacks.

More Related Videos

Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

6.6K
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.5K

Related Experiment Videos

Last Updated: Feb 5, 2026

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.3K
Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

6.6K
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.5K

Area of Science:

  • Pulmonology
  • Pharmacology
  • Clinical Trials

Background:

  • Asthma exacerbations represent a significant burden on patients and healthcare systems.
  • Current treatments for asthma exacerbations have limitations.
  • Metformin, a widely used antidiabetic drug, has shown potential anti-inflammatory effects.

Purpose of the Study:

  • To evaluate the efficacy of metformin in reducing the frequency and severity of asthma exacerbations.
  • To synthesize evidence from randomized controlled trials on metformin for asthma management.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials.
  • Search of major biomedical databases for relevant studies.
  • Assessment of risk of bias and data synthesis.

Main Results:

  • Data synthesis is pending the identification and inclusion of relevant trials.
  • The review will quantify the effect of metformin on primary outcomes such as exacerbation rates and secondary outcomes like lung function and quality of life.

Conclusions:

  • The potential role of metformin in asthma management requires rigorous evaluation.
  • Evidence from this review will inform clinical practice and future research directions regarding metformin for asthma.