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Related Experiment Video

Updated: Feb 5, 2026

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation
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Outcomes of a Clinic-Based PCIMT Program on Upper Extremity Movement Quality.

Regan L Blankenship1, Lori Breeden2, Katy Mitchell3

  • 1Regan L. Blankenship, DHSc, MS, OTR/L, is Assistant Professor, Division of Occupational Therapy, Medical University of South Carolina, Charleston; blankenr@musc.edu.

The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association
|February 3, 2026
PubMed
Summary

Clinic-based pediatric constraint-induced movement therapy (PCIMT) significantly improved upper extremity movement in children with hemiparesis. This therapy enhances range of motion, accuracy, dexterity, and fluency, supporting its clinical use.

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Area of Science:

  • Pediatric rehabilitation
  • Neuroscience
  • Occupational therapy

Background:

  • Pediatric constraint-induced movement therapy (PCIMT) is an emerging treatment for unilateral hemiparesis in children.
  • Limited evidence exists on the outcomes of clinic-based PCIMT programs.

Purpose of the Study:

  • To evaluate the effectiveness of a clinic-based PCIMT program on upper extremity movement quality in children with unilateral hemiparesis.

Main Methods:

  • Quantitative, retrospective study involving 26 children (ages 2.5-8) with unilateral hemiparesis.
  • A 3-week clinic-based PCIMT program (ACQUIREc protocol) was implemented.
  • Upper extremity movement quality was assessed using the Melbourne Assessment of Unilateral Upper Limb Function-2 (MUIAlert-2) pre- and post-intervention.

Main Results:

  • Significant improvements were observed in range of motion, accuracy, dexterity, and fluency post-intervention.
  • Manual Abilities Classification Scale (MACS) and Mini-MACS levels predicted accuracy improvement but not other movement quality measures.

Conclusions:

  • Clinic-based PCIMT programs can significantly enhance upper extremity movement quality in children with unilateral hemiparesis.
  • Findings support the clinical application of PCIMT and suggest further research into optimizing protocols and outcome prediction based on classification levels.