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SASBDB reaches 5000 data sets: empowering open science and next-generation SAS analysis.
Clement E Blanchet1, Aleksi Sutinen1, Melissa A Graewert1
1European Molecular Biology Laboratory (EMBL), Hamburg, Germany.
Acta Crystallographica. Section D, Structural Biology
|February 3, 2026
Summary
The Small-Angle Scattering Biological Data Bank (SASBDB) now has 5000 entries, supporting open and reusable biological small-angle scattering data for reproducibility and analysis.
Area of Science:
- Structural Biology
- Biophysics
- Data Science
Background:
- The Small-Angle Scattering Biological Data Bank (SASBDB) supports open and reusable biological small-angle scattering (SAS) data.
- It has been developed through community efforts for over a decade.
- SASBDB provides curated experimental scattering profiles and metadata.
Purpose of the Study:
- To highlight the SASBDB's milestone of 5000 entries.
- To emphasize its role in enabling data sharing, reproducibility, and comparative analysis.
- To showcase its importance for benchmarking, reanalysis, and method development.
Main Methods:
- Curating experimental scattering profiles.
- Collecting metadata on samples and experimental conditions.
- Integrating structural models with scattering data.
Main Results:
- SASBDB reached 5000 entries, demonstrating significant community support.
- The archive facilitates transparent data sharing and reproducibility.
- It serves as a resource for evaluating modeling approaches and developing new methods.
Conclusions:
- SASBDB is a foundational infrastructure for biological small-angle scattering.
- Its growing content supports current and future data-driven and machine-learning approaches.
- The milestone underscores the value of open and reusable scientific data.
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