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Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
Published on: January 30, 2017
H4N6 avian influenza virus in Iran: first isolation and molecular insights
Mohsen Bashashati1, Mohammad Hossein Fallah Mehrabadi2, Leila Moradi Haghgou2
1Department of Avian Disease Research and Diagnostics, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran. m.bashashati@rvsri.ac.ir.
Abstract:
The rapid evolutionary dynamics of avian influenza viruses (AIVs) enable frequent genetic drift and reassortment, posing ongoing challenges to both poultry and public health. In this study, we report the isolation of an H4N6 virus strain (Duck/Qom/02-663/2024) from a commercial duck farm in Iran. BLAST analysis indicated that, while the surface glycoproteins and nucleoprotein closely matched those of other H4N6 viruses, the remaining gene segments were more closely related to other subtypes, suggesting a potentially reassortant virus. Phylogenetic analysis classified the isolate within the Eurasian lineage. These findings underscore the importance of continuous surveillance of AIVs in both wild and domestic bird populations.
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