Related Experiment Video
Updated: Feb 5, 2026

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
18FAl-NOTA-FAPI PET/CT Outperforms 18F-FDG PET/CT in Detecting Gastrointestinal Metastasis of Lobular Breast
Annan Zhang1, Ming Zu2, Yanpeng Ma3
1Departments of Nuclear Medicine.
None:
A 57-year-old woman with a history of right breast cancer surgery 22 years prior presented with CT findings of gastric and intestinal wall thickening, accompanied by mild-to-moderate FDG uptake on 18F-FDG PET/CT. Pathological results showed lobular breast cancer metastasis. The lesions showed significantly higher uptake on 18FAl-NOTA-FAPI PET/CT, and an additional sternal metastasis was identified.
Related Concept Videos
Radiological Investigation I: X-ray and CT
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

