Value of Optimal Follow-up in Patients with Pulmonary Embolism (OFUPE): Study Protocol for a Prospective Randomized...

Area of Science:

• Cardiology
• Pulmonology
• Clinical Trials

Background:

• Advances in pulmonary thromboembolism (PTE) diagnosis and treatment have improved survival rates.
• Increased survival necessitates a focus on long-term prognosis and holistic patient management.
• Effective post-acute care requires systematic follow-up and continuous monitoring for PTE patients.

Purpose of the Study:

• To compare the efficacy of an optimal follow-up strategy against routine follow-up in patients with acute PTE.
• To evaluate the role of holistic management, including telemedicine, in improving long-term outcomes for PTE survivors.
• To assess the impact of systematic follow-up protocols on all-cause mortality and adverse events in PTE patients.

Main Methods:

• Prospective randomized study (Optimal Follow-Up in Pulmonary Embolism - OFUPE).
• 1:1 randomization of acute PTE patients into two groups: optimal follow-up and routine follow-up.
• Optimal follow-up includes education, individualized care planning, and telemedicine support.
• Routine follow-up involves standard monitoring.
• Primary endpoints: all-cause mortality and adverse events.

Main Results:

• Results are pending as the study is ongoing.
• The study is designed to provide data on the effectiveness of the optimal follow-up strategy.

Conclusions:

• The OFUPE study will elucidate the benefits of a systematic, holistic approach to post-PTE care.
• Findings are expected to inform clinical guidelines for long-term management of pulmonary thromboembolism.
• The study aims to establish a framework for continuous monitoring and support of PTE patients.