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Updated: Feb 5, 2026

Spatial Separation of Molecular Conformers and Clusters
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Molecular tuning of DNA framework-programmed silicification by cationic silica cluster attachment

Xinxin Jing1,2, Haozhi Wang1, Jianxiang Huang3,4

  • 1State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

Proceedings of the National Academy of Sciences of the United States of America
|February 3, 2026
PubMed
Summary

Scientists discovered ultrastable cationic silica clusters (CSCs) that assemble on DNA nanostructures. This breakthrough offers a new model for amorphous silica mineralization, enabling precise control over silica-based material design.

Keywords:
DNA nanotechnologyamorphous silicabiominerals

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