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Published on: January 15, 2017
WUSED Study: Wake-Up Strokes in the Emergency Department.
Yashraj Kale1, Manogya Ranjan1, Prabhakar Thirumal Appaswamy2
1Department of Emergency Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Wake-up stroke patients often present with motor deficits and speech issues. Hemorrhagic strokes in these patients are linked to younger age, higher blood pressure, and hypoxia upon arrival.
Area of Science:
- Neurology
- Emergency Medicine
- Stroke Research
Background:
- Wake-up stroke (WS) presents diagnostic challenges due to unknown onset time.
- Emergency department (ED) physicians and neurologists require better understanding for optimal WS therapy.
Purpose of the Study:
- To profile patients with wake-up stroke presenting to the emergency department.
- To compare predictors of hemorrhagic versus ischemic stroke in WS patients.
Main Methods:
- Retrospective study conducted in a tertiary care hospital ED in South India.
- Analysis of hospital electronic database for patients with WS from January 2017 to June 2017.
Main Results:
- 88 out of 346 stroke patients (25.4%) had WS; mean age 59 years, 73.9% males.
- Ischemic strokes (82%) were most common, predominantly anterior circulation.
- Hemorrhagic stroke patients were younger, had higher systolic blood pressure, and more hypoxia on arrival.
Conclusions:
- WS constitutes a significant portion of stroke presentations.
- Demographic and clinical factors differ between hemorrhagic and ischemic WS subtypes.
- Further research is needed to refine WS diagnosis and treatment strategies.
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