Assessment of Recurrent Stroke Frequency and Risk Factors in Patients with Carotid Stenosis Undergoing Symptomatic...

Carotid stenosis increases the risk of ischemic stroke in the ipsilateral carotid artery territory, contributing to 10-20% of all transient ischemic attacks and strokes. Carotid revascularization, including carotid endarterectomy and stenting, was performed to reduce this risk. This study aimed to evaluate the frequency of recurrent stroke in patients with symptomatic and asymptomatic carotid stenosis and to assess the risk factors for recurrent stroke after carotid stenting.

This study included 330 patients aged >18 who underwent carotid stenting between January 2016 and April 2023. Patient data, including imaging and e-pulse records, were reviewed to identify whether recurrent strokes occurred after the procedure. This study aimed to determine the incidence of recurrent stroke and investigate its potential risk factors.

Among the 330 patients who underwent carotid revascularization, 35 developed recurrent stroke during the follow-up period. No significant difference was found in hypertension between the two groups (P = 0.453). However, diabetes was significantly more prevalent in the stroke group (P = 0.023). Univariate logistic regression revealed that the risk of recurrent stroke in patients was 2.27 times higher (95% CI: 1.10-4.68) than in nondiabetic patients (P = 0.026). Additionally, patients with a history of stroke had a 2.25 times higher risk of recurrent stroke (95% CI: 1.02-4.96) than those without a history of stroke (P = 0.045).

Carotid stenting is an effective treatment for preventing recurrent strokes. The risk of recurrent stroke is higher in patients with diabetes and a history of stroke. Close monitoring, including regular assessment of antiplatelet therapy and lipid management, is essential for reducing the risk of recurrent stroke in high-risk patients.