Related Experiment Video
Updated: Feb 5, 2026

Preparation of Acute Slices from Dorsal Hippocampus for Whole-Cell Recording and Neuronal Reconstruction in the Dentate Gyrus of Adult Mice
Published on: April 3, 2021
Rhythmic modulation of the dorsal hippocampus during specific within-trial segments links to future behavior
Maeve C Bottoms1, Jesse T Miles2,3, Sheri J Y Mizumori4,2
1Department of Psychology, University of Washington, Seattle, Washington 98195, USA.
Abstract:
It is not yet clear how dorsal hippocampal rhythms contribute specific information that impacts future behavior. Using a spatial set-shifting task that requires animals to behave flexibly and continuously adapt to different spatial strategies, we found that beta power increased after incorrect choices. Higher beta and gamma power after reward feedback was linked with greater accuracy on the next trial, scaling with rhythm power. These results highlight the importance of relating hippocampal rhythms to multiple within-trial segments to better understand how individual rhythms may differentially support future behaviors.
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