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Updated: Feb 5, 2026

Ferric Chloride-induced Murine Thrombosis Models
Published on: September 5, 2016
Two new mycobactins, mycobactins U and V, and their ferric complexes isolated from Mycolicibacterium septicum IFM
Yasumasa Hara1,2,3, Yuki Matsuoka4, Akiko Takaya4,5
1Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki, 761-0795, Kagawa, Japan. hara.yasumasa@kagawa-u.ac.jp.
Abstract:
Two new mycobactins, U (1) and V (3), were isolated with ferric-1 (2) and ferric-3 (4) from the culture extracts of Mycolicibacterium septicum IFM 12283. The structures of compounds 1-4 were elucidated via spectral studies, including various NMR analyses. The absolute configurations of compounds 1-4 were deduced by comparing their circular dichroism (CD) spectra with those of mycobactin H (5) and ferric-mycobactin H (6). These compounds exhibited cytotoxicity against the MH7A rheumatoid fibroblast-like synovial cell line.
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