Related Experiment Video
Updated: Feb 5, 2026

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents
Published on: August 14, 2018
Asymmetric Metaphyseal Cones for AORI Type 2 Medial Defects in Tibial Plateau Fractures during Acute TKA
Yi Ren1, Chloe E H Scott2,3, Shuqiao Xie4
1Institute for Bioengineering, School of Engineering, The University of Edinburgh, Edinburgh, UK.
Abstract:
This finite element study evaluated the biomechanical performance of asymmetric metaphyseal cones in large Type 2a/b medial tibial defects simulating medial tibial plateau fractures during acute total knee arthroplasty, to determine thresholds for safe clinical application. A finite element model of a tibia with tibial baseplate, asymmetric metaphyseal cone, and short cemented stem was utilised. Sixteen medial fracture patterns (AORI Type 2a/b defects) were simulated with unsupported surface area ratios from 0% to 60%. Two physiological loading scenarios (walking and stair descending) were applied. Implant stability was evaluated through tangential and normal micromotions at the bone-cone coating interface, with thresholds of 150 μm for osseointegration and 50 μm for long-term stability. Bone mechanical response was quantified through principal strain distributions. Tangential and normal micromotions increased with defect size but remained below critical thresholds, with maximum tangential micromotion of 36 μm during stair descending at a 60% ratio. Micromotions and bone strain demonstrated a threshold effect at approximately 52% ratio, beyond which both parameters increased substantially. At a 60% ratio during stair descending, 0.11% and 0.12% of bone volume exceeded tension and compression thresholds, respectively. Asymmetric metaphyseal cones maintain sufficient stability for managing medial tibial plateau fractures during acute total knee arthroplasty, with interface micromotion below critical thresholds even in severe defects. The recommended maximum unsupported area ratio is 52%, providing a clear quantitative threshold for clinical decision-making.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Rotation of Asymmetric Top
The relationship between the angular momentum of any rigid body and its angular velocity, both of which are vectors, involves the moment of inertia. The moment of inertia is a scalar quantity only for spherically symmetric...
Asymmetric Lipid Bilayer
Lumber Defects
Shakes are minor fractures that run along or across the wood's annual rings, while wane is...
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...

