Related Experiment Video
Updated: Feb 5, 2026
07:50
Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
999
Incidence, Risk Factors, and Temporal Trends of Tongue Cancer: A Population-Based Study
Junjie Huang1,2, Wing Sze Pang1, Claire Chenwen Zhong1
1The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China.
Cancer Medicine
|February 4, 2026
Summary
Tongue cancer incidence varies globally, with South-Central Asia bearing the highest burden. Lifestyle factors like smoking and alcohol contribute to higher rates in males, emphasizing the need for intervention.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Tongue cancer is the most common intraoral malignancy worldwide.
- Understanding its global burden, risk factors, and incidence trends is crucial for public health strategies.
Purpose of the Study:
- To investigate the global burden and epidemiological trends of tongue cancer.
- To identify key risk factors associated with tongue cancer incidence.
- To analyze demographic and geographic variations in tongue cancer rates.
Main Methods:
- Utilized data from Global Cancer Observatory, Cancer Incidence in Five Continents Plus, and Global Burden of Disease.
- Employed linear regression to analyze the association between incidence and risk factors.
- Assessed temporal trends using Average Annual Percentage Change (AAPC) with 95% confidence intervals.
Main Results:
- Identified 151,338 global tongue cancer cases with an age-standardized rate (ASR) of 1.7/100,000.
- Highest ASRs were in South-Central Asia (3.4), Northern America (2.3), and Northern Europe (2.1).
- Incidence correlated significantly with smoking, alcohol consumption, and dietary factors; males showed higher ASRs (2.6) than females (0.86).
Conclusions:
- Significant geographical disparities in tongue cancer burden exist, notably highest in South-Central Asia.
- Higher male incidence is linked to smoking and alcohol use, underscoring the importance of lifestyle modifications.
- Global incidence shows an increasing trend, with few exceptions like the Philippines.
Related Concept Videos
01:26Factors Affecting the Risk of Infection
13.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.5K
01:01Tongue
3.0K
The human tongue is a fascinating and complex organ, responsible for various essential functions such as swallowing, speech, and taste. It is also subject to various conditions and diseases. In this article, we delve into the anatomy of the tongue, its roles, and some common conditions that can affect it.
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
3.0K
01:08Prevalence and Incidence
1.9K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.9K
02:04Conservation of Small Populations
17.4K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.4K
00:57Population Growth
28.6K
Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
28.6K
01:10Tip-of-the-Tongue Phenomenon
524
The tip-of-the-tongue (TOT) phenomenon is a cognitive experience characterized by a temporary inability to retrieve specific information from memory despite having a strong feeling of knowing the information. Although individuals cannot access the target word or detail, they frequently recall related elements, such as its initial letter, syllable count, or context. This partial retrieval often causes frustration, as one might recognize a familiar face or know that a name starts with a specific...
524