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Updated: Feb 5, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Syphilitic Uveitis-Associated Chiasmal Optic Neuritis Presenting As Bitemporal Hemianopia-Like Visual Field Defects
Tomoya Ishibe1, Mami Otsuka1, Maho Itotani1
1Department of Ophthalmology, Oita University, Oita, JPN.
Abstract:
Syphilis is a systemic infectious disease that can involve both ocular tissues and the central nervous system, with syphilitic uveitis representing one of its ocular manifestations. We report a rare case of syphilitic uveitis occurring in conjunction with chiasmal optic neuritis. A 48-year-old man presented with blurred vision in the right eye and was found to have bilateral acute syphilitic posterior placoid chorioretinitis with vitreous opacity in the left eye. Visual field testing demonstrated bitemporal hemianopia-like defects, and magnetic resonance imaging revealed enhancement of the optic chiasm. Serologic testing confirmed syphilis. Oral amoxicillin therapy resulted in complete resolution of the inflammation and recovery of vision. This case highlights that bitemporal hemianopia in patients with syphilitic uveitis may reflect concurrent chiasmal involvement rather than uveitic pathology alone, underscoring the importance of early diagnosis and appropriate treatment are crucial for achieving favorable visual outcomes.
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