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Updated: Feb 5, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Obstructive sleep apnea in adults]
M A J van Looij1, S K Singh1, G Aarab2
1The ear, nose and throat department of the OLVG hospital in Amsterdam.
Abstract:
Obstructive sleep apnea is a prevalent disorder characterized by symptoms such as snoring, apneas, excessive daytime sleepiness, and a variety of other clinical complaints. Dental comorbidities, including bruxism and xerostomia, are also commonly observed. If left untreated, OSA may result in significant cardiovascular and metabolic complications. The diagnosis is established through a sleep study, following a comprehensive clinical history and physical examination. Drug-Induced Sleep Endoscopy provides additional diagnostic insight, particularly in patients being evaluated for potential surgical intervention. Treatment planning takes into consideration not only the objective clinical findings and results of ancillary testing but also the patient s expectations and preferences. Treatment options include lifestyle intervention, continuous positive airway pressure, mandibular advancement devices, positional therapy, and surgical interventions.
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