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Thermal Measurement Techniques in Analytical Microfluidic Devices
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An active-matrix digital microfluidic device based on surfactant-mediated electro-dewetting.

Xinying Xie1, Qining Leo Wang2, Runxiao Shi1

  • 1The Hong Kong University of Science and Technology, Hong Kong. xiexinying@ust.hk.

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|February 4, 2026
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Summary
This summary is machine-generated.

This study introduces an active-matrix electro-dewetting digital microfluidics (DMF) device. It enables precise droplet manipulation using low voltage, paving the way for scalable DMF applications.

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Area of Science:

  • Microfluidics
  • Materials Science
  • Electrical Engineering

Background:

  • Digital microfluidics (DMF) commonly uses electrowetting for droplet manipulation.
  • Existing electro-dewetting DMF devices are limited by direct-drive electrode control, restricting scalability.
  • Surfactant-mediated electro-dewetting offers electrical control over droplet hydrophobicity.

Purpose of the Study:

  • To develop an active-matrix (AM) electro-dewetting DMF device with enhanced electrode control.
  • To enable low-voltage droplet manipulation using continuous current drive.
  • To overcome the electrode number limitations of direct-drive DMF systems.

Main Methods:

  • Fabrication of an AM electro-dewetting DMF device utilizing indium-tin-zinc oxide top-gate self-aligned thin-film transistors.
  • Integration of thin-film transistors within the cell circuit for addressing and driving droplets.
  • Demonstration of droplet transport, splitting, and merging using the developed AM DMF device.

Main Results:

  • Successful implementation of an active-matrix electro-dewetting DMF device.
  • Demonstrated low-voltage droplet manipulation (transport, split, merge) via continuous current.
  • Validation of the AM architecture for scalable electro-dewetting DMF systems.

Conclusions:

  • The developed AM electro-dewetting DMF device effectively manipulates droplets at low voltages.
  • This technology significantly expands the number of independently controllable electrodes in DMF.
  • It establishes a foundation for advanced, large-scale electro-dewetting DMF applications.