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Updated: Feb 6, 2026

The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse
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The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse

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M2-sEVs-based immunotherapy for alleviation of osteoarthritis-related pain by regulating synovial macrophage NGF

Jiashuo Liu1, Luhao Sun1, Lei Luo1,2

  • 1Department of Orthopedic Surgery, Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Nanomedicine (London, England)
|February 4, 2026
PubMed
Abstract

Keywords:
Osteoarthritismacrophagesnotchpainsmall extracellular vesicles

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