Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptide Bonds02:43

Peptide Bonds

83.2K
A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
83.2K
Plasticity00:58

Plasticity

3.1K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
3.1K
Plasticizers01:31

Plasticizers

372
Water-reducers, or plasticizers, are chemical admixtures used in concrete to improve strength and workability. These additives reduce the water-cement ratio without compromising workability, lower the cement content while maintaining the same workability, or increase workability to assist concrete placement in inaccessible areas.
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
372
Common Ion Effect03:24

Common Ion Effect

46.9K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
46.9K
Plastic Behavior01:21

Plastic Behavior

580
A material's elastic behavior is characterized by the disappearance of stress once the load is removed, allowing the material to return to its original state. However, when stress surpasses the yield point, yielding commences, marking the onset of plastic deformation or permanent set. This change from elastic to plastic behavior is influenced by the peak stress value and the duration before the load is removed. An intriguing observation occurs when a specimen is loaded, unloaded, and...
580
Plastic Deformations01:14

Plastic Deformations

455
It is essential to understand how structural members behave under plastic deformation when the bending stress exceeds the material's yield strength. This state of deformation permanently alters the shape of the member, in contrast to the linear elastic behavior observed before yielding. The strain at any point in the member is expressed in terms of maximum strain. Notably, the neutral axis, which coincides with the centroid during elastic bending, shifts away from the centroid under plastic...
455

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Headgroup-Dependent Thermotropic and Lyotropic Phase Behavior and Emulsifying Behavior of Guerbet Branched-Chain Glycolipids.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Structural Topology-based Electrostatic Model (STEM) Reveals Ion-Coordination Exchange as a Driver of RNA Folding Dynamics.

bioRxiv : the preprint server for biology·2026
Same author

Nanostructure and Collagen-Stimulating Activity of Cationic Pentapeptide Lipopeptides.

Journal of peptide science : an official publication of the European Peptide Society·2026
Same author

C-terminally engineered nucleopeptide-based soft materials exhibiting antibacterial and antifungal efficacy against multi-drug-resistant strains.

Organic & biomolecular chemistry·2026
Same author

Polyelectrolyte-like Behavior, pH-Dependent Self-Assembly, and Emulsion Stabilizing Properties of a Model Surfactant-like Peptide Bearing Pyridine Groups.

Biomacromolecules·2026
Same author

Lysine containing amphiphilic peptide-based non-cytotoxic soft materials with potential antifungal and antibacterial activities for 3D cell culture.

Soft matter·2026

Related Experiment Video

Updated: Feb 6, 2026

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.7K

Ion-Induced Morphological Plasticity in a Self-Assembling Peptide Hydrogel.

Biplab Mondal1, Tanushree Mondal1, Anushree Sinha2

  • 1School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & 2B Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.

Langmuir : the ACS Journal of Surfaces and Colloids
|February 4, 2026
PubMed
Summary

This study presents a peptide hydrogel that changes shape in response to different metal ions. This ion-specific adaptability allows for tunable properties and enhanced mechanical strength in adaptive hydrogel systems.

More Related Videos

Cultivation of Human Neural Progenitor Cells in a 3-dimensional Self-assembling Peptide Hydrogel
11:01

Cultivation of Human Neural Progenitor Cells in a 3-dimensional Self-assembling Peptide Hydrogel

Published on: January 11, 2012

17.0K
Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids
10:23

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids

Published on: May 3, 2024

1.5K

Related Experiment Videos

Last Updated: Feb 6, 2026

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.7K
Cultivation of Human Neural Progenitor Cells in a 3-dimensional Self-assembling Peptide Hydrogel
11:01

Cultivation of Human Neural Progenitor Cells in a 3-dimensional Self-assembling Peptide Hydrogel

Published on: January 11, 2012

17.0K
Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids
10:23

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids

Published on: May 3, 2024

1.5K

Area of Science:

  • Materials Science
  • Supramolecular Chemistry
  • Biomaterials Engineering

Background:

  • Hydrogels are versatile soft materials with applications in various fields.
  • Controlling hydrogel morphology and properties at the nanoscale is crucial for advanced applications.
  • Peptide-based hydrogels offer biocompatibility and tunable self-assembly characteristics.

Purpose of the Study:

  • To investigate the stimuli-responsive behavior of a peptide hydrogel in the presence of different metal ions.
  • To elucidate the ion-specific mechanisms governing morphological and mechanical changes in the hydrogel.
  • To explore the potential of this adaptive hydrogel for biomedical and sensing applications.

Main Methods:

  • Transmission electron microscopy (TEM), atomic force microscopy (AFM), small-angle X-ray scattering (SAXS), and X-ray diffraction (XRD) for structural analysis.
  • Atomistic molecular dynamics simulations to understand nanoscale transitions.
  • Mechanical testing to evaluate hydrogel properties after ion exposure.

Main Results:

  • Monovalent and trivalent ions induced a morphological transformation from nanofibers to nanospheres.
  • Divalent ions triggered syneresis (shrinking) and a shift to nanoribbon morphology.
  • Ion-peptide interactions were confirmed to control nanoscale morphology, network architecture, and mechanical performance.
  • Hydrogels with mono- or trivalent ions showed enhanced thermal and mechanical stability.
  • Syneresis in divalent ion-containing gels acted as a postassembly strengthening mechanism, increasing stiffness.

Conclusions:

  • Peptide hydrogels exhibit remarkable ion-specific stimuli-responsiveness and morphological plasticity.
  • Ion-peptide interactions are key to orchestrating the material's properties at multiple length scales.
  • This adaptive hydrogel system offers tunable physicochemical properties and opens avenues for advanced applications in biomedicine and sensing.