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The role of artificial intelligence in managing COVID-19 and long COVID: a narrative review

Bikash Kanti Sarkar1, Ambuj Kumar1

  • 1Department of Computer Science and Engineering, Birla Institute of Technology, Ranchi, India.

Osong Public Health and Research Perspectives
|February 4, 2026
PubMed

Insights

Long COVID (LC) significantly impacts multiple organ systems, affecting survivors' quality of life. Artificial intelligence (AI) shows potential in managing these long COVID effects, despite ethical considerations.

Area of Science:

  • Medical Research
  • Health Informatics
  • Artificial Intelligence in Medicine

Background:

  • The COVID-19 pandemic caused widespread health issues, including persistent symptoms in survivors known as long COVID (LC).
  • LC leads to long-term damage across multiple organ systems, significantly reducing survivors' quality of life.
  • There is a growing need to understand LC's multifaceted impacts and explore innovative solutions.

Purpose of the Study:

  • To increase awareness of organ system damage caused by long COVID.
  • To highlight the potential of artificial intelligence (AI) in addressing long COVID challenges.
  • To discuss ethical and practical concerns associated with AI implementation in healthcare.

Main Methods:

  • A narrative review of 69 relevant studies identified through comprehensive database searches (Embase, PubMed, Web of Science, Scopus).
  • Expert review of selected literature by at least two health science specialists.
  • Analysis of organ system impacts and AI's role based on authors' insights.

Main Results:

  • Long COVID results in lasting damage to various human organ systems.
  • Artificial intelligence presents significant potential for improving long COVID care and management.
  • Ethical issues like data privacy and algorithmic bias are critical considerations for AI in LC.

Conclusions:

  • Long COVID poses a significant, persistent threat to organ health and quality of life.
  • AI offers promising avenues for mitigating the adverse effects of long COVID.
  • Careful consideration of ethical implications is essential for the responsible deployment of AI in long COVID care.

Keywords:
Artificial-intelligence-roleConcernsDamageHuman-organ-systemsLong-COVID

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